cell^tool TIRFM System - Key Features

cell^tool TIRFM System

TIRF microscopy system based on the cell^M and cell^R imaging stations

cell^tool TIRFM is based on a modular multi-port illuminator for up to three lasers and a MT10 or MT20 widefield fluorescence light source. This extension of the cell^M and cell^R imaging stations allows for laser based high resolution cell surface and membrane studies with the possibility of simultaneous widefield observation. The control of the TIRFM illuminator is integrated into the 'Experiment Manager' of cell^M and cell^R software, so in addition to highest quality TIRF observation cell^tool TIRFM offers all the powerful options of the cell* imaging stations.

The cell^tool TIRFM is available as a complete turn-key solution or as an add-on for existing cell^M or cell^R imaging systems.



  • The only 4 line system with true simultaneous acquisition
  • Motorized control of TIRF angles
  • Precise adjustment of incident angle
  • Software calculation of penetration depth
  • Software based laser attenuation
  • Integrated Point FRAP optics for 1st laser line
  • Seamless widefield/TIRF switching
  • Six dedicated TIRF lenses, world’s highest NA of 1.65
  • 405 – 640nm laser systems
  • TIRF and widefield or 100% widefield with 340nm Transmission
  • 25mm filter access for each laser line
  • Adjustable field stop for each laser line
  • Rigid single billet Aluminum frame
  • Single molecule and membrane research

Watch cell^ TIRF videos:-


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