cell^R - Key Features


cell^R - Imaging Station

High-speed imaging for live cell microscopy

cell^R supports the Olympus IX and BX microscopes and consists of the unique all-in-one illumination system MT20, highly sensitive digital cameras and a hyper-precision hardware control board. The cell^R imaging software is a powerful all-embracing platform that features the Experiment Manager: an intuitive and user-friendly graphical interface to set up experiments in a convenient and concise way

 

 


Summary:-

  • Fast multi-fluorescence 3D time-lapse imaging
  • Minimised photo-bleaching
  • Graphical experiment set-up
  • Data archiving, processing and analysis

  Multi-function all-in-one illumination system MT20
The MT20 contains a fast filter wheel (minimal switch 58 ms) with 8 positions and a fast attenuator with 14 grades of illumination intensity. The built-in shutter has the exceptional on/off time of 1 ms and basically eliminates off-acquisition photobleaching. Two types of light sources are optional: a high-stability 150W Xe arc burner or a very stable 150W Hg/Xe mixed gas arc burner. The light is coupled via a single quartz light fibre into the microscope.

   Hyper-precision real-time experiment control
An additional independent plug-in CPU board ensures interrupt-free data uptake by the cell^R imaging computer during an experiment. Experiment control and sub-millisecond timing precision are maintained while changing hardware settings. Filter wheel, attenuator and shutter of the MT20 are optimally synchronised with the camera, an optional piezo Z-drive and other peripherals. All modules work in parallel.

  Digital Cameras: high resolution and sensitivity
Besides the XM10, several latest-generation interline transfer CCD models of reputable manufacturers are supported. For low-light acquisition electron multiplier CCD (EM-CCD) and back-thinned CCD cameras can be used.

  cell^R imaging software for acquisition, documentation, processing, and analysis
The all-embracing platform offers a host of processing and analysis functions and several unique features: the Experiment Manager – an intuitive graphical interface for experiment planning, set-up and execution; Spectral Unmixing – a unique tool for colour resolution enhancement; a sophisticated, structured database for archiving and documentation.

  Experiment Manager – intuitive graphical experiment planning, set-up and execution
This very easy to learn clearly structured interface allows an intuitive assembly of experiment plans based on drag&drop assembly of icons that represent simple commands, groups of commands or entire sub-experiments. Individual exposure times, attenuation values and ROIs can be set for each image acquisition command. Experiment plans are automatically stored together with the image data in the database.